Resolution 2100 of 2025: A New Approach to Addressing the Consumption of Psychoactive Substances in Colombia
Monday 27 October 2025
On October 14, 2025, the Ministry of Health and Social Protection of Colombia issued Resolution 2100, marking a milestone in public policy related to the consumption of psychoactive substances. This regulation establishes a comprehensive approach that seeks to transform the way the country approaches prevention, risk and harm reduction, and care for the consumption of psychoactive substances, both licit and illicit. The resolution has a time horizon of the period 2025–2033 and is framed in the national public health and human rights strategy.
The decision to adopt this policy responds to the need to face the growing challenge represented by the consumption of psychoactive substances in Colombia. According to data from the Ministry of Health, an increase in consumption rates has been observed, especially among the young population, which has generated a negative impact on public health and social security in the country. Furthermore, the prevalence of psychoactive substance consumption has been identified as a risk factor for the development of mental illnesses and associated disorders.
In this context, Resolution 2100 seeks to offer a coherent and coordinated response to this phenomenon, aligning the actions of the State with the principles of public health, human rights and a gender approach. The adopted policy aims to guarantee access to quality health services for people who consume psychoactive substances, promoting their well-being and social reintegration.
Objectives of Resolution 2100
Resolution 2100 establishes the following main objectives:

1. Prevention of psychoactive substance use: Implement educational and community strategies that discourage the start of use, especially in vulnerable populations.
2. Reducing risks and harms associated with consumption:Offer health services that minimize the negative consequences of consumption, such as syringe exchange programs, overdose care and treatment of related diseases.
3. Comprehensive care for people who consume psychoactive substances: Guarantee access to mental health, rehabilitation and social reintegration services, with a person-centered approach that respects their rights.
4. Institutional and community strengthening:Train health professionals and communities so that they can identify, treat and support people affected by the use of psychoactive substances.
5. Continuous monitoring and evaluation:Establish monitoring mechanisms that allow policies and programs to be adjusted according to the evolution of the phenomenon and the needs of the population.
Implemented Strategies

To achieve these objectives, Resolution 2100 proposes a series of key strategies:
– Development of educational programs: Implement awareness campaigns in schools, universities and communities, focused on the risks of consumption and the promotion of healthy lifestyles.
– Access to specialized health services: Expand the coverage of mental health and addiction services, ensuring that they are accessible, confidential and of quality.
– Strengthening community networks: Support the creation of support networks among peers and community groups that facilitate the social integration of people who consume psychoactive substances.
– Training of health personnel: Provide continuous training to doctors, psychologists, social workers and other health professionals in the management of the consumption of psychoactive substances and in the application of approaches based on human rights.
– Implementation of intersectoral public policies:Coordinate actions between different sectors of the State, such as education, justice, work and social welfare, to comprehensively address the phenomenon of consumption.
Expected Impact

The implementation of Resolution 2100 is expected to have the following positive impacts:
– Reduction in the prevalence of consumption: Decrease the number of people who begin or maintain the consumption of psychoactive substances.
– Improvement in public health: Reduce the incidence of diseases related to consumption, such as HIV/AIDS, hepatitis and mental disorders.
– Strengthening the health system: Improve the capacity of the health system to care for people with problems related to the use of psychoactive substances.
– Effective social reintegration: Facilitate social inclusionand labor of people who have overcome their dependency, contributing to their well-being and the development of the country.
Implementation Challenges

Despite the significant advances that Resolution 2100 represents, there are several challenges in its implementation:
– Social stigma: Rejection and discrimination towards people who use psychoactive substances can hinder their access to health services and their social reintegration.
– Limited resources: Insufficient allocation of financial and human resources can hinder the expansion and sustainability of proposed programs.
– Interinstitutional coordination: The lack of coordination between different State entities can generate duplication of efforts and dispersion of resources.
– Cultural resistance: Cultural norms and values that criminalize the use of psychoactive substances can make it difficult to adopt human rights-based approaches.
Below you will find in detail the Resolution 2100 of 2025
Conclusion
Resolution 2100 of 2025 represents an important step towards a more humane, scientific and effective public policy in the management of the consumption of psychoactive substances in Colombia. By adopting a comprehensive approach that combines prevention, care and risk reduction, we seek not only to improve the health of affected people, but also to contribute to the construction of a more inclusive and equitable society. The successful implementation of this policy will depend on the commitment of all social actors and the State to overcome the challenges and guarantee that people’s rights are respected and protected.
