{"id":1343,"date":"2024-02-01T22:20:43","date_gmt":"2024-02-02T03:20:43","guid":{"rendered":"https:\/\/invitronews.com\/trending-topic\/evaluation-of-a-commercial-multiplex-pcr-unyvero-i60\/"},"modified":"2024-02-02T15:21:52","modified_gmt":"2024-02-02T20:21:52","slug":"evaluation-of-a-commercial-multiplex-pcr-unyvero-i60","status":"publish","type":"post","link":"https:\/\/invitronews.com\/en\/evaluation-of-a-commercial-multiplex-pcr-unyvero-i60\/","title":{"rendered":"Evaluation of a commercial multiplex PCR Unyvero i60\u00ae."},"content":{"rendered":"

Introduction:<\/strong> The development of sonication over the past \u0303 years has increased the sensitivity of conventional cultures for the diagnosis of Prosthetic Joint Infections (PJI). However, the development of a new kit, designed \u0303 specifically for the diagnosis of IPAs could be a significant breakthrough in this field.<\/p>\n

Methods:<\/strong> all prostheses removed from patients between May 2014 and May 2015 were sent to
\nculture using a processing protocol that includes implant sonication. In addition, 180 microliters of the sonication liquid was used to perform multiplex PCR (Unyvero i60\u00ae).
\nA comparison of the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) was performed.
\n(VPN). The study was approved by the Clinical Research Ethics Committee.
\nResults: 88 prostheses from 68 patients were analyzed (1.29 prostheses\/patient). The prostheses studied
\nwere knees (n = 55), total hip (n = 26), partial hip (n = 5), and shoulder (n = 2). Twenty-nine patients were diagnosed with IPA (15 chronic, 12 acute and 2 hematogenous). In 24 cases, the result was
\nThe PCR test was positive, with all but 1 of these being from patients with IPA criteria. In addition, 9 resistance mechanisms were detected in 5 samples. The Unyvero i60\u00ae system showed slight results.
\nsuperior to culture in both specificity and PPV.<\/p>\n

Conclusions:<\/strong> The Unyvero i60\u00ae system may have a role in the rapid diagnosis of IPA due to its high specificity and PPV. However, despite these results, culture should be performed to detect organisms not detected by the system.<\/p>\n

Read the complete article in its original language Evaluation commercial multiplex PCR Unyvero i60<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Introduction: The development of sonication over the past \u0303 years has increased the sensitivity of conventional cultures for the diagnosis of Prosthetic Joint Infections (PJI). However, the development of a new kit, designed \u0303 specifically for the diagnosis of IPAs could be a significant breakthrough in this field. Methods: all prostheses removed from patients between  … Read more <\/i><\/a><\/p>\n","protected":false},"author":2,"featured_media":591,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_glsr_average":0,"_glsr_ranking":0,"_glsr_reviews":0,"footnotes":""},"categories":[50],"tags":[],"class_list":["post-1343","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-notes","type_content-article","edition-edition-1","outstanding-regular"],"yoast_head":"\nEvaluation of a commercial multiplex PCR Unyvero i60\u00ae. - Invitro News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/invitronews.com\/en\/evaluation-of-a-commercial-multiplex-pcr-unyvero-i60\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evaluation of a commercial multiplex PCR Unyvero i60\u00ae. - Invitro News\" \/>\n<meta property=\"og:description\" content=\"Introduction: The development of sonication over the past \u0303 years has increased the sensitivity of conventional cultures for the diagnosis of Prosthetic Joint Infections (PJI). However, the development of a new kit, designed \u0303 specifically for the diagnosis of IPAs could be a significant breakthrough in this field. Methods: all prostheses removed from patients between  … Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/invitronews.com\/en\/evaluation-of-a-commercial-multiplex-pcr-unyvero-i60\/\" \/>\n<meta property=\"og:site_name\" content=\"Invitro News\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/AnnarHealthTechnologies\" \/>\n<meta property=\"article:published_time\" content=\"2024-02-02T03:20:43+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-02-02T20:21:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/invitronews.com\/wp-content\/uploads\/2022\/12\/invitro-news-revista-3d-render-background-with-cell-elements-medical-concept-with-abstract-molecules-1.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"1500\" \/>\n\t<meta property=\"og:image:height\" content=\"844\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ELAN PEREA\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@invitro_edit\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ELAN PEREA\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/invitronews.com\/en\/evaluation-of-a-commercial-multiplex-pcr-unyvero-i60\/\",\"url\":\"https:\/\/invitronews.com\/en\/evaluation-of-a-commercial-multiplex-pcr-unyvero-i60\/\",\"name\":\"Evaluation of a commercial multiplex PCR Unyvero i60\u00ae. - 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